This experiment mainly optimizes Agaricus Blazei Polipeptide (ABP) extraction technology and evaluates the protection effect on aging mice. In this study, a new single component, M 3 KD, isolated and purified from Agaricus Blazei. The aging mouse model was established using D-galactose. After the ABP administration, the contents of total antioxidant capacity (T-AOC), malondialdehyde (MDA), catalase (cat), and reactive oxygen species changed significantly. Through immunofluorescence staining, observed that ABP can reduce brain tissue changes. The expression of the generation of genes was analyzed by RNA-SEQ.
A total of 295 genes expressed differently filtered in the ABP Gen Group.rt-QPCR verify the important gene and show that the level of MRNA HSPH1, Trim32, HNRNPA1, and Grik5 expression increased significantly, and people from APOE, ATP1A3, STXBP1, and MAPK8IP1 decreased significantly. West Blotting shows that the level of expression of KAPE1 and P53 protein is significantly lower, while the level of protein expression of NRF2, HO-1, HSPH1, and TRIM32 is significantly higher in the ABP group.
ABP plays an anti-aging role in a rat aging model. Specific work mechanisms may be related to the expression regulations of the KAPE1 / NRF2 / P53 signaling path and related factors. Practical application: This research can contribute to the development of ABP as functional food or food supplements for anti-aging in the future.
Carboxyl-terminal polypeptide fragment from MUC16 Combing Stathmin1 promotes migration and bile cancer cell invasion
CA-125, encoded by Gen MUC16, is responsible for various types of tumor metastasis. However, related mechanisms are still unclear. We have set new ways to reveal gallbladder cancer metastasis related to the serum level CA-125 through C-terminal polypeptides from Gen16 production. MUC16 C-terminal polypeptides significantly promote bile cancer cell migration and in vitro invasion. The mass spectrum indicates that the interaction of MUC16 terminal C fragment with the C-STATHmin1 terminal domain inhibits STATHMIN1 phosphorylation to promote combinations with tubulins.
STATHMIN1 Knockdown Inhibits migration and invasion of bile cancer cells in vitro and metastasis in vivo lungs caused by polypeptides Terminal C-terminal MUC16. The level of high expression of MUC16C is consistent with STATHMIN1 is also confirmed in the gallbladder cancer tissue. Our study revealed the mechanism that underlies the gallbladder cancer metastasis related to the level of CA-125, which is useful for CA-125 in the diagnosis and therapy of gallbladder cancer.
Localization of vasoactive polypeptide receptor 1 (VPAC1) in neuroendocrine hypothalamic neuroendocrine neurons; Potential role in circadian prolactin secretion
Prolactin (PRL) is a versatile hormone and presents various physiological functions other than lactation. The release of the PRL from lactotrof in the hypophysis owned in mice is proven to be released with a circadian pattern depending on the physiological state of the animal. The release of the Circadian PRL seems to be a complex involving tonic inhibition by dopamine (DA) neurons in lactotrof and one or even several release factors. Because of the pattern of release of circadian PRL, neurons in the suprachiasmatic nucleus (SCN), “brain clock,” and especially neurons that express neuropeptide vasoactive polypeptide intestine (VIP), have been advised to be involved in the circadian regulation.

In this study, we use immunohistochemical fluorescence, in hybridization histochemistry situ, confocal microscope, three-dimensional reconstruction, and very specific antibodies to visualize the occurrence of VIP 1 and 2 receptors (VPAC1 and VPAC2) in the stained mouse hypothalamic section in combination with VIP , Oxytocin (OXT), Arginine Vasopresin (AVP), and DA (Tyrosine hydroxylase, th). We show that VIP fiber is likely to come from the ventral part of the SCN project to OXT neurons in the magnocelluler part of nucleus paraventricular (PVN).
In PVN, VIP fibers found in the application close to Oxt Neurons exclusively express VPAC1 receptors. Next, we show that Oxt neurons or AVP neurons do not express VPAC2 receptors. The expression of VPAC receptors is also found in blood vessels but not in neurons that express AVP or th. These findings indicate that VIP signaling from the SCN does not directly target neurons involved in the PLL secretion. Furthermore, the findings support the idea that the VIP from neurons in the SCN can regulate the release of circadian oxt in pituitary neurons or posterior modulation as the release factor involved in the temperature regulation of lactotrof.
Pancreas polypeptides but not other members of the Neuropeptide Y family show a moderate relationship with anxiety felt in a fat man
Neuropeptide Y (NPY), Peptide Tyrosine Tyrosine (PYY), and Pancreatic Polypeptide (PP) is an important mediator in two-way communication along the intestinal axis. Most famous for their role in taste rules and their food intake is considered to play an important role in the development of obesity. In addition, evidence of installation shows regulatory functions in anxiety, mood and stress resistance with gender potential differences. In this study, we examined the association of NPY, PYY, and PP plasma levels with anxiety, depression and stress felt in obesity patients.
We analyzed 144 inpatients (90 women, 54 men, BMI: 49.4 kg / m2) in naturalistic care settings for obesity and somatic and mental comorbidity. Fasting blood samples were taken, and the patient completed the psychometric self-assessment questionnaire (GAD-7, PHQ-9, PSQ-20) in the first week after entering and before exiting. The plasma concentration of peptides was measured by Elisa. Women showed higher anxiety (GAD-7: 8.13 ± 5.67 vs 5.93 ± 5.42, p = 0.04) and stress scores (PSQ-20: 52.62 ± 23.5 vs 41.23 ± 0.01 ) than men. In the longitudinal analysis of women with increasing clinically relevant anxiety (≥ 5 points at GAD-7, P <0.001) also showed a significant increase in depression (PHQ-9: 38%, p = 0.002) and PSQ-20 score (23) %, p = 0.005) while male patients who enhanced anxiety only increased in the tension of the PSQ-20 subscale (34%, p = 0.02).
In the man we observed the positive correlation of PP with anxiety scores (GAD-7: R = 0.41, p = 0.007) and with age (r = 0.49, p = 0.001) when entered while NPY correlated negatively with age (r = -0.38), p = 0.01). Instead, there was no significant association (P> 0.05) on the subject of women in cross-sectional and in longitudinal analysis. In conclusion, women who suffer from terrible obesity show greater psychological comorbidity and considerable interaction between them.
PTCHD2 Antibody |
25404-100ul |
SAB |
100ul |
EUR 468 |
PTCHD2 Antibody |
6637-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism. |
PTCHD2 Antibody |
6637-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism. |
PTCHD2 Antibody |
4915-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism. |
PTCHD2 Antibody |
4915-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism. |
PTCHD2 Antibody |
4925-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism. |
PTCHD2 Antibody |
4925-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism. |
Polyclonal PTCHD2 Antibody |
AMR09590G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD2 . This antibody is tested and proven to work in the following applications: |
Polyclonal PTCHD2 Antibody |
AMR09591G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD2 . This antibody is tested and proven to work in the following applications: |
Polyclonal PTCHD2 Antibody |
AMR09592G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD2 . This antibody is tested and proven to work in the following applications: |
Human PTCHD2 shRNA Plasmid |
20-abx961520 |
Abbexa |
|
|
|
PTCHD2 ORF Vector (Human) (pORF) |
ORF028512 |
ABM |
1.0 ug DNA |
Ask for price |
Ptchd2 ORF Vector (Mouse) (pORF) |
ORF055152 |
ABM |
1.0 ug DNA |
EUR 1886.4 |
Polyclonal PTCHD2 Antibody (N-Terminus) |
AMR09593G |
Leading Biology |
0.05mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD2 (N-Terminus). This antibody is tested and proven to work in the following applications: |
Ptchd2 3'UTR GFP Stable Cell Line |
TU167223 |
ABM |
1.0 ml |
Ask for price |
PTCHD2 3'UTR GFP Stable Cell Line |
TU069132 |
ABM |
1.0 ml |
EUR 1672.8 |
PTCHD2 sgRNA CRISPR Lentivector set (Human) |
K1748901 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Ptchd2 sgRNA CRISPR Lentivector set (Mouse) |
K3185201 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
PTCHD2 Protein Vector (Human) (pPM-C-HA) |
PV114048 |
ABM |
500 ng |
Ask for price |
PTCHD2 Protein Vector (Mouse) (pPM-C-HA) |
PV220608 |
ABM |
500 ng |
EUR 2766 |
PTCHD2 Protein Vector (Human) (pPB-C-His) |
PV114046 |
ABM |
500 ng |
Ask for price |
PTCHD2 Protein Vector (Human) (pPB-N-His) |
PV114047 |
ABM |
500 ng |
Ask for price |
PTCHD2 Protein Vector (Human) (pPM-C-His) |
PV114049 |
ABM |
500 ng |
Ask for price |
PTCHD2 Protein Vector (Mouse) (pPB-C-His) |
PV220606 |
ABM |
500 ng |
EUR 2766 |
PTCHD2 Protein Vector (Mouse) (pPB-N-His) |
PV220607 |
ABM |
500 ng |
EUR 2766 |
PTCHD2 Protein Vector (Mouse) (pPM-C-His) |
PV220609 |
ABM |
500 ng |
EUR 2766 |
Ptchd2 3'UTR Luciferase Stable Cell Line |
TU117223 |
ABM |
1.0 ml |
Ask for price |
PTCHD2 3'UTR Luciferase Stable Cell Line |
TU019132 |
ABM |
1.0 ml |
EUR 1672.8 |
PTCHD2 sgRNA CRISPR Lentivector (Human) (Target 1) |
K1748902 |
ABM |
1.0 ug DNA |
EUR 184.8 |
PTCHD2 sgRNA CRISPR Lentivector (Human) (Target 2) |
K1748903 |
ABM |
1.0 ug DNA |
EUR 184.8 |
PTCHD2 sgRNA CRISPR Lentivector (Human) (Target 3) |
K1748904 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd2 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K3185202 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd2 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K3185203 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd2 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K3185204 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Mouse Patched domain- containing protein 2, Ptchd2 ELISA KIT |
ELI-43078m |
Lifescience Market |
96 Tests |
EUR 1038 |
Human Patched domain- containing protein 2, PTCHD2 ELISA KIT |
ELI-44851h |
Lifescience Market |
96 Tests |
EUR 988.8 |
PTCHD2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
K1748905 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
Ptchd2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
K3185205 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
PTCHD2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
K1748906 |
ABM |
1.0 ug DNA |
EUR 200.4 |
PTCHD2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
K1748907 |
ABM |
1.0 ug DNA |
EUR 200.4 |
PTCHD2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
K1748908 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
K3185206 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
K3185207 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
K3185208 |
ABM |
1.0 ug DNA |
EUR 200.4 |
PTCH1 Peptide |
43-308P |
ProSci |
0.1 mg |
EUR 405.6 |
PTCH Peptide |
46-245P |
ProSci |
0.1 mg |
EUR 405.6 |
Description: (CT) PTCH Peptide |
PTCH Peptide |
46-246P |
ProSci |
0.1 mg |
EUR 405.6 |
Description: (IN) PTCH Peptide |
PTCH1 Blocking Peptide |
33R-9121 |
Fitzgerald |
100 ug |
EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PTCH1 antibody, catalog no. 70R-6354 |
PTCH2 Blocking Peptide |
33R-4790 |
Fitzgerald |
100 ug |
EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PTCH2 antibody, catalog no. 70R-6356 |
PTCHD1 siRNA |
20-abx930255 |
Abbexa |
|
|
|
PTCHD1 siRNA |
20-abx930256 |
Abbexa |
|
|
|
PTCHD3 siRNA |
20-abx930258 |
Abbexa |
|
|
|
PTCHD3 siRNA |
20-abx930259 |
Abbexa |
|
|
|
PTCHD4 siRNA |
20-abx930260 |
Abbexa |
|
|
|
PTCHD4 siRNA |
20-abx930261 |
Abbexa |
|
|
|
PTCD2 Peptide |
43-220P |
ProSci |
0.1 mg |
EUR 405.6 |
PTCD2 Peptide |
43-224P |
ProSci |
0.1 mg |
EUR 405.6 |
PTCHD3 Antibody |
R34501-100UG |
NSJ Bioreagents |
100 ug |
EUR 339.15 |
Description: Additional name(s) for this target protein: Patched domain containing 3 |
PTCHD1 Antibody |
R33444-100UG |
NSJ Bioreagents |
100 ug |
EUR 339.15 |
Description: Additional name(s) for this target protein: Patched domain containing 1 |
Ptchd1 ORF Vector (Rat) (pORF) |
ORF074258 |
ABM |
1.0 ug DNA |
EUR 607.2 |
PTCHD1 cloning plasmid |
CSB-CL839383HU-10ug |
Cusabio |
10ug |
EUR 921.6 |
|
Description: A cloning plasmid for the PTCHD1 gene. |
PTCHD3 cloning plasmid |
CSB-CL668587HU-10ug |
Cusabio |
10ug |
EUR 568.8 |
|
Description: A cloning plasmid for the PTCHD3 gene. |
PTCHD1 ORF Vector (Human) (pORF) |
ORF014194 |
ABM |
1.0 ug DNA |
EUR 424.8 |
PTCHD3 ORF Vector (Human) (pORF) |
ORF014195 |
ABM |
1.0 ug DNA |
EUR 424.8 |
PTCHD4 ORF Vector (Human) (pORF) |
ORF028513 |
ABM |
1.0 ug DNA |
Ask for price |
Ptchd1 ORF Vector (Mouse) (pORF) |
ORF055151 |
ABM |
1.0 ug DNA |
EUR 607.2 |
Ptchd3 ORF Vector (Mouse) (pORF) |
ORF055153 |
ABM |
1.0 ug DNA |
EUR 607.2 |
Ptchd1 3'UTR GFP Stable Cell Line |
TU167222 |
ABM |
1.0 ml |
Ask for price |
Ptchd3 3'UTR GFP Stable Cell Line |
TU167224 |
ABM |
1.0 ml |
Ask for price |
PTCHD1 3'UTR GFP Stable Cell Line |
TU069131 |
ABM |
1.0 ml |
EUR 5540.4 |
PTCHD3 3'UTR GFP Stable Cell Line |
TU069133 |
ABM |
1.0 ml |
EUR 1672.8 |
Ptchd1 3'UTR GFP Stable Cell Line |
TU267013 |
ABM |
1.0 ml |
Ask for price |
Ptchd3 3'UTR GFP Stable Cell Line |
TU267014 |
ABM |
1.0 ml |
Ask for price |
Human PTCHD1 shRNA Plasmid |
20-abx965253 |
Abbexa |
|
|
|
Mouse PTCHD1 shRNA Plasmid |
20-abx980711 |
Abbexa |
|
|
|
Mouse PTCHD4 shRNA Plasmid |
20-abx984190 |
Abbexa |
|
|
|
Mouse PTCHD3 shRNA Plasmid |
20-abx978291 |
Abbexa |
|
|
|
Human PTCHD3 shRNA Plasmid |
20-abx967609 |
Abbexa |
|
|
|
Human PTCHD4 shRNA Plasmid |
20-abx968324 |
Abbexa |
|
|
|
PTCHD1 Protein Vector (Rat) (pPM-C-HA) |
PV297032 |
ABM |
500 ng |
EUR 1399.2 |
PTCHD1 Protein Vector (Rat) (pPB-C-His) |
PV297030 |
ABM |
500 ng |
EUR 1399.2 |
PTCHD1 Protein Vector (Rat) (pPB-N-His) |
PV297031 |
ABM |
500 ng |
EUR 1399.2 |
PTCHD1 Protein Vector (Rat) (pPM-C-His) |
PV297033 |
ABM |
500 ng |
EUR 1399.2 |
PTCHD1 Protein Vector (Human) (pPM-C-HA) |
PV056775 |
ABM |
500 ng |
EUR 577.2 |
PTCHD3 Protein Vector (Human) (pPM-C-HA) |
PV056779 |
ABM |
500 ng |
EUR 577.2 |
PTCHD4 Protein Vector (Human) (pPM-C-HA) |
PV114052 |
ABM |
500 ng |
Ask for price |
PTCHD1 Protein Vector (Mouse) (pPM-C-HA) |
PV220604 |
ABM |
500 ng |
EUR 1278 |
PTCHD3 Protein Vector (Mouse) (pPM-C-HA) |
PV220612 |
ABM |
500 ng |
EUR 1278 |
Polyclonal PTCHD3 Antibody (C-term) |
APR03561G |
Leading Biology |
0.1ml |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD3 (C-term). This antibody is tested and proven to work in the following applications: |
PTCHD1 Protein Vector (Human) (pPB-C-His) |
PV056773 |
ABM |
500 ng |
EUR 577.2 |
PTCHD1 Protein Vector (Human) (pPB-N-His) |
PV056774 |
ABM |
500 ng |
EUR 577.2 |
PTCHD1 Protein Vector (Human) (pPM-C-His) |
PV056776 |
ABM |
500 ng |
EUR 577.2 |
PTCHD3 Protein Vector (Human) (pPB-C-His) |
PV056777 |
ABM |
500 ng |
EUR 577.2 |
PTCHD3 Protein Vector (Human) (pPB-N-His) |
PV056778 |
ABM |
500 ng |
EUR 577.2 |
PTCHD3 Protein Vector (Human) (pPM-C-His) |
PV056780 |
ABM |
500 ng |
EUR 577.2 |
PTCHD4 Protein Vector (Human) (pPB-C-His) |
PV114050 |
ABM |
500 ng |
Ask for price |
PTCHD4 Protein Vector (Human) (pPB-N-His) |
PV114051 |
ABM |
500 ng |
Ask for price |
PTCHD4 Protein Vector (Human) (pPM-C-His) |
PV114053 |
ABM |
500 ng |
Ask for price |
PTCHD1 Protein Vector (Mouse) (pPB-C-His) |
PV220602 |
ABM |
500 ng |
EUR 1278 |
PTCHD1 Protein Vector (Mouse) (pPB-N-His) |
PV220603 |
ABM |
500 ng |
EUR 1278 |
PTCHD1 Protein Vector (Mouse) (pPM-C-His) |
PV220605 |
ABM |
500 ng |
EUR 1278 |
PTCHD3 Protein Vector (Mouse) (pPB-C-His) |
PV220610 |
ABM |
500 ng |
EUR 1278 |
PTCHD3 Protein Vector (Mouse) (pPB-N-His) |
PV220611 |
ABM |
500 ng |
EUR 1278 |
PTCHD3 Protein Vector (Mouse) (pPM-C-His) |
PV220613 |
ABM |
500 ng |
EUR 1278 |
Ptchd1 3'UTR Luciferase Stable Cell Line |
TU117222 |
ABM |
1.0 ml |
Ask for price |
Ptchd3 3'UTR Luciferase Stable Cell Line |
TU117224 |
ABM |
1.0 ml |
Ask for price |
PTCHD1 3'UTR Luciferase Stable Cell Line |
TU019131 |
ABM |
1.0 ml |
EUR 5540.4 |
PTCHD3 3'UTR Luciferase Stable Cell Line |
TU019133 |
ABM |
1.0 ml |
EUR 1672.8 |
Ptchd1 3'UTR Luciferase Stable Cell Line |
TU217013 |
ABM |
1.0 ml |
Ask for price |
Ptchd3 3'UTR Luciferase Stable Cell Line |
TU217014 |
ABM |
1.0 ml |
Ask for price |
Ptchd1 sgRNA CRISPR Lentivector set (Rat) |
K6195001 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
PTCHD1 sgRNA CRISPR Lentivector set (Human) |
K1748801 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
PTCHD3 sgRNA CRISPR Lentivector set (Human) |
K1749001 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Ptchd1 sgRNA CRISPR Lentivector set (Mouse) |
K3867201 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Ptchd3 sgRNA CRISPR Lentivector set (Mouse) |
K3246401 |
ABM |
3 x 1.0 ug |
EUR 406.8 |
Ptchd1 sgRNA CRISPR Lentivector (Rat) (Target 1) |
K6195002 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd1 sgRNA CRISPR Lentivector (Rat) (Target 2) |
K6195003 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd1 sgRNA CRISPR Lentivector (Rat) (Target 3) |
K6195004 |
ABM |
1.0 ug DNA |
EUR 184.8 |
PTCHD1 sgRNA CRISPR Lentivector (Human) (Target 1) |
K1748802 |
ABM |
1.0 ug DNA |
EUR 184.8 |
PTCHD1 sgRNA CRISPR Lentivector (Human) (Target 2) |
K1748803 |
ABM |
1.0 ug DNA |
EUR 184.8 |
PTCHD1 sgRNA CRISPR Lentivector (Human) (Target 3) |
K1748804 |
ABM |
1.0 ug DNA |
EUR 184.8 |
PTCHD3 sgRNA CRISPR Lentivector (Human) (Target 1) |
K1749002 |
ABM |
1.0 ug DNA |
EUR 184.8 |
PTCHD3 sgRNA CRISPR Lentivector (Human) (Target 2) |
K1749003 |
ABM |
1.0 ug DNA |
EUR 184.8 |
PTCHD3 sgRNA CRISPR Lentivector (Human) (Target 3) |
K1749004 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd1 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K3867202 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd1 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K3867203 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd1 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K3867204 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd3 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K3246402 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd3 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K3246403 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Ptchd3 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K3246404 |
ABM |
1.0 ug DNA |
EUR 184.8 |
Polyclonal PTCHD1 Antibody (internal region) |
APR13016G |
Leading Biology |
0.1 mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PTCHD1 (internal region). This antibody is tested and proven to work in the following applications: |
Polyclonal PTCHD3 Antibody (internal region) |
APG00729G |
Leading Biology |
0.1mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PTCHD3 (internal region). This antibody is tested and proven to work in the following applications: |
Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat) |
K6195005 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
PTCHD4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
LV773435 |
ABM |
1.0 ug DNA |
EUR 1104 |
PTCHD4 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC) |
LV773439 |
ABM |
1.0 ug DNA |
EUR 1104 |
PTCHD1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
K1748805 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
PTCHD3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
K1749005 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
K3867205 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
Ptchd3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
K3246405 |
ABM |
3 x 1.0 ug |
EUR 451.2 |
Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1) |
K6195006 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2) |
K6195007 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3) |
K6195008 |
ABM |
1.0 ug DNA |
EUR 200.4 |
PTCHD4 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a) |
LV773440 |
ABM |
1.0 ug DNA |
EUR 1104 |
Human Patched domain- containing protein 1, PTCHD1 ELISA KIT |
ELI-37910h |
Lifescience Market |
96 Tests |
EUR 988.8 |
Mouse Patched domain- containing protein 1, Ptchd1 ELISA KIT |
ELI-30411m |
Lifescience Market |
96 Tests |
EUR 1038 |
Human Patched domain- containing protein 3, PTCHD3 ELISA KIT |
ELI-30412h |
Lifescience Market |
96 Tests |
EUR 988.8 |
Mouse Patched domain- containing protein 3, Ptchd3 ELISA KIT |
ELI-15541m |
Lifescience Market |
96 Tests |
EUR 1038 |
TKD Peptide (Hsp70 Peptide) (Hsp70 Peptide) |
SIH-118A |
Stressmarq |
1 mg |
EUR 374.4 |
|
Description: The substance TKD Peptide (Hsp70 Peptide) is a hsp70 peptide. It is synthetically produced and has a purity of >98%. The pure substance is solid which is In aqueous solution. |
Patched Domain-Containing Protein 3 (PTCHD3) Antibody |
abx026245-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
Patched Domain-Containing Protein 3 (PTCHD3) Antibody |
abx026245-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
Patched Domain-Containing Protein 1 (PTCHD1) Antibody |
abx431630-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
Patched Domain-Containing Protein 3 (PTCHD3) Antibody |
abx433196-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
PTCHD1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
K1748806 |
ABM |
1.0 ug DNA |
EUR 200.4 |
PTCHD1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
K1748807 |
ABM |
1.0 ug DNA |
EUR 200.4 |
PTCHD1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
K1748808 |
ABM |
1.0 ug DNA |
EUR 200.4 |
PTCHD3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
K1749006 |
ABM |
1.0 ug DNA |
EUR 200.4 |
PTCHD3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
K1749007 |
ABM |
1.0 ug DNA |
EUR 200.4 |
PTCHD3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
K1749008 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
K3867206 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
K3867207 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
K3867208 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
K3246406 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
K3246407 |
ABM |
1.0 ug DNA |
EUR 200.4 |
Ptchd3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
K3246408 |
ABM |
1.0 ug DNA |
EUR 200.4 |
TKD Peptide (Hsp70 Peptide): FITC (Hsp70 Peptide) |
SIH-119A |
Stressmarq |
1 mg |
EUR 430.8 |
|
Description: The substance TKD Peptide (Hsp70 Peptide): FITC is a hsp70 peptide. It is synthetically produced and has a purity of >98%. The pure substance is solid which is In aqueous solution. |
PTCHD4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA) |
LV773436 |
ABM |
1.0 ug DNA |
EUR 1104 |
PTCHD4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro) |
LV773437 |
ABM |
1.0 ug DNA |
EUR 1173.6 |
PTCHD4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro) |
LV773438 |
ABM |
1.0 ug DNA |
EUR 1173.6 |
TKD Peptide (Hsp70 Peptide) |
abx076809-1mg |
Abbexa |
1 mg |
EUR 594 |
|
Rat Peptide YY (PYY) Peptide |
20-abx068453 |
Abbexa |
-
EUR 744.00
-
EUR 326.40
-
EUR 2230.80
-
EUR 878.40
-
EUR 543.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Human Connecting Peptide (C-Peptide) Peptide |
abx670072-05mg |
Abbexa |
0.5 mg |
EUR 678 |
|
Human Peptide YY (PYY) Peptide |
20-abx068451 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2013.60
-
EUR 811.20
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mouse Peptide YY (PYY) Peptide |
20-abx068452 |
Abbexa |
-
EUR 710.40
-
EUR 309.60
-
EUR 2131.20
-
EUR 844.80
-
EUR 526.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
TKD Peptide (Hsp70 Peptide) (FITC) |
abx076810-1mg |
Abbexa |
1 mg |
EUR 678 |
|
Rat Connecting Peptide (C-Peptide) Peptide (OVA) |
20-abx651058 |
Abbexa |
-
EUR 510.00
-
EUR 276.00
-
EUR 1378.80
-
EUR 594.00
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Dog Peptide YY (PYY) Peptide (OVA) |
20-abx651198 |
Abbexa |
-
EUR 427.20
-
EUR 260.40
-
EUR 1178.40
-
EUR 526.80
-
EUR 343.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Pig Peptide YY (PYY) Peptide (OVA) |
20-abx651200 |
Abbexa |
-
EUR 427.20
-
EUR 260.40
-
EUR 1178.40
-
EUR 526.80
-
EUR 343.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Even though we only observed the PP association with anxiety and age with NPY and PP in men, suggesting the possibility of the effect of sex hormones on the NPY system. However, an increase in anxiety scores does not lead to significant changes in NPY.