This experiment mainly optimizes Agaricus Blazei Polipeptide (ABP) extraction technology and evaluates the protection effect on aging mice. In this study, a new single component, M 3 KD, isolated and purified from Agaricus Blazei. The aging mouse model was established using D-galactose. After the ABP administration, the contents of total antioxidant capacity (T-AOC), malondialdehyde (MDA), catalase (cat), and reactive oxygen species changed significantly. Through immunofluorescence staining, observed that ABP can reduce brain tissue changes. The expression of the generation of genes was analyzed by RNA-SEQ.

A total of 295 genes expressed differently filtered in the ABP Gen Group.rt-QPCR verify the important gene and show that the level of MRNA HSPH1, Trim32, HNRNPA1, and Grik5 expression increased significantly, and people from APOE, ATP1A3, STXBP1, and MAPK8IP1 decreased significantly. West Blotting shows that the level of expression of KAPE1 and P53 protein is significantly lower, while the level of protein expression of NRF2, HO-1, HSPH1, and TRIM32 is significantly higher in the ABP group.

ABP plays an anti-aging role in a rat aging model. Specific work mechanisms may be related to the expression regulations of the KAPE1 / NRF2 / P53 signaling path and related factors. Practical application: This research can contribute to the development of ABP as functional food or food supplements for anti-aging in the future.

Carboxyl-terminal polypeptide fragment from MUC16 Combing Stathmin1 promotes migration and bile cancer cell invasion

CA-125, encoded by Gen MUC16, is responsible for various types of tumor metastasis. However, related mechanisms are still unclear. We have set new ways to reveal gallbladder cancer metastasis related to the serum level CA-125 through C-terminal polypeptides from Gen16 production. MUC16 C-terminal polypeptides significantly promote bile cancer cell migration and in vitro invasion. The mass spectrum indicates that the interaction of MUC16 terminal C fragment with the C-STATHmin1 terminal domain inhibits STATHMIN1 phosphorylation to promote combinations with tubulins.

STATHMIN1 Knockdown Inhibits migration and invasion of bile cancer cells in vitro and metastasis in vivo lungs caused by polypeptides Terminal C-terminal MUC16. The level of high expression of MUC16C is consistent with STATHMIN1 is also confirmed in the gallbladder cancer tissue. Our study revealed the mechanism that underlies the gallbladder cancer metastasis related to the level of CA-125, which is useful for CA-125 in the diagnosis and therapy of gallbladder cancer.

Localization of vasoactive polypeptide receptor 1 (VPAC1) in neuroendocrine hypothalamic neuroendocrine neurons; Potential role in circadian prolactin secretion

Prolactin (PRL) is a versatile hormone and presents various physiological functions other than lactation. The release of the PRL from lactotrof in the hypophysis owned in mice is proven to be released with a circadian pattern depending on the physiological state of the animal. The release of the Circadian PRL seems to be a complex involving tonic inhibition by dopamine (DA) neurons in lactotrof and one or even several release factors. Because of the pattern of release of circadian PRL, neurons in the suprachiasmatic nucleus (SCN), “brain clock,” and especially neurons that express neuropeptide vasoactive polypeptide intestine (VIP), have been advised to be involved in the circadian regulation.

In this study, we use immunohistochemical fluorescence, in hybridization histochemistry situ, confocal microscope, three-dimensional reconstruction, and very specific antibodies to visualize the occurrence of VIP 1 and 2 receptors (VPAC1 and VPAC2) in the stained mouse hypothalamic section in combination with VIP , Oxytocin (OXT), Arginine Vasopresin (AVP), and DA (Tyrosine hydroxylase, th). We show that VIP fiber is likely to come from the ventral part of the SCN project to OXT neurons in the magnocelluler part of nucleus paraventricular (PVN).

In PVN, VIP fibers found in the application close to Oxt Neurons exclusively express VPAC1 receptors. Next, we show that Oxt neurons or AVP neurons do not express VPAC2 receptors. The expression of VPAC receptors is also found in blood vessels but not in neurons that express AVP or th. These findings indicate that VIP signaling from the SCN does not directly target neurons involved in the PLL secretion. Furthermore, the findings support the idea that the VIP from neurons in the SCN can regulate the release of circadian oxt in pituitary neurons or posterior modulation as the release factor involved in the temperature regulation of lactotrof.

Pancreas polypeptides but not other members of the Neuropeptide Y family show a moderate relationship with anxiety felt in a fat man

Neuropeptide Y (NPY), Peptide Tyrosine Tyrosine (PYY), and Pancreatic Polypeptide (PP) is an important mediator in two-way communication along the intestinal axis. Most famous for their role in taste rules and their food intake is considered to play an important role in the development of obesity. In addition, evidence of installation shows regulatory functions in anxiety, mood and stress resistance with gender potential differences. In this study, we examined the association of NPY, PYY, and PP plasma levels with anxiety, depression and stress felt in obesity patients.

We analyzed 144 inpatients (90 women, 54 men, BMI: 49.4 kg / m2) in naturalistic care settings for obesity and somatic and mental comorbidity. Fasting blood samples were taken, and the patient completed the psychometric self-assessment questionnaire (GAD-7, PHQ-9, PSQ-20) in the first week after entering and before exiting. The plasma concentration of peptides was measured by Elisa. Women showed higher anxiety (GAD-7: 8.13 ± 5.67 vs 5.93 ± 5.42, p = 0.04) and stress scores (PSQ-20: 52.62 ± 23.5 vs 41.23 ± 0.01 ) than men. In the longitudinal analysis of women with increasing clinically relevant anxiety (≥ 5 points at GAD-7, P <0.001) also showed a significant increase in depression (PHQ-9: 38%, p = 0.002) and PSQ-20 score (23) %, p = 0.005) while male patients who enhanced anxiety only increased in the tension of the PSQ-20 subscale (34%, p = 0.02).

In the man we observed the positive correlation of PP with anxiety scores (GAD-7: R = 0.41, p = 0.007) and with age (r = 0.49, p = 0.001) when entered while NPY correlated negatively with age (r = -0.38), p = 0.01). Instead, there was no significant association (P> 0.05) on the subject of women in cross-sectional and in longitudinal analysis. In conclusion, women who suffer from terrible obesity show greater psychological comorbidity and considerable interaction between them.

PTCHD2 Antibody
25404-100ul	SAB	100ul	EUR 468

PTCHD2 Antibody
6637-002mg	ProSci	0.02 mg	EUR 206.18
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.

PTCHD2 Antibody
6637-01mg	ProSci	0.1 mg	EUR 523.7
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.

PTCHD2 Antibody
4915-002mg	ProSci	0.02 mg	EUR 206.18
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.

PTCHD2 Antibody
4915-01mg	ProSci	0.1 mg	EUR 523.7
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.

PTCHD2 Antibody
4925-002mg	ProSci	0.02 mg	EUR 206.18
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.

PTCHD2 Antibody
4925-01mg	ProSci	0.1 mg	EUR 523.7
Description: PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.

Polyclonal PTCHD2 Antibody
AMR09590G	Leading Biology	0.1 mg	EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD2 . This antibody is tested and proven to work in the following applications:

Polyclonal PTCHD2 Antibody
AMR09591G	Leading Biology	0.1 mg	EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD2 . This antibody is tested and proven to work in the following applications:

Polyclonal PTCHD2 Antibody
AMR09592G	Leading Biology	0.1 mg	EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD2 . This antibody is tested and proven to work in the following applications:

Human PTCHD2 shRNA Plasmid
20-abx961520	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

PTCHD2 ORF Vector (Human) (pORF)
ORF028512	ABM	1.0 ug DNA	Ask for price

Ptchd2 ORF Vector (Mouse) (pORF)
ORF055152	ABM	1.0 ug DNA	EUR 1886.4

Polyclonal PTCHD2 Antibody (N-Terminus)
AMR09593G	Leading Biology	0.05mg	EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD2 (N-Terminus). This antibody is tested and proven to work in the following applications:

Ptchd2 3'UTR GFP Stable Cell Line
TU167223	ABM	1.0 ml	Ask for price

PTCHD2 3'UTR GFP Stable Cell Line
TU069132	ABM	1.0 ml	EUR 1672.8

PTCHD2 sgRNA CRISPR Lentivector set (Human)
K1748901	ABM	3 x 1.0 ug	EUR 406.8

Ptchd2 sgRNA CRISPR Lentivector set (Mouse)
K3185201	ABM	3 x 1.0 ug	EUR 406.8

PTCHD2 Protein Vector (Human) (pPM-C-HA)
PV114048	ABM	500 ng	Ask for price

PTCHD2 Protein Vector (Mouse) (pPM-C-HA)
PV220608	ABM	500 ng	EUR 2766

PTCHD2 Protein Vector (Human) (pPB-C-His)
PV114046	ABM	500 ng	Ask for price

PTCHD2 Protein Vector (Human) (pPB-N-His)
PV114047	ABM	500 ng	Ask for price

PTCHD2 Protein Vector (Human) (pPM-C-His)
PV114049	ABM	500 ng	Ask for price

PTCHD2 Protein Vector (Mouse) (pPB-C-His)
PV220606	ABM	500 ng	EUR 2766

PTCHD2 Protein Vector (Mouse) (pPB-N-His)
PV220607	ABM	500 ng	EUR 2766

PTCHD2 Protein Vector (Mouse) (pPM-C-His)
PV220609	ABM	500 ng	EUR 2766

Ptchd2 3'UTR Luciferase Stable Cell Line
TU117223	ABM	1.0 ml	Ask for price

PTCHD2 3'UTR Luciferase Stable Cell Line
TU019132	ABM	1.0 ml	EUR 1672.8

PTCHD2 sgRNA CRISPR Lentivector (Human) (Target 1)
K1748902	ABM	1.0 ug DNA	EUR 184.8

PTCHD2 sgRNA CRISPR Lentivector (Human) (Target 2)
K1748903	ABM	1.0 ug DNA	EUR 184.8

PTCHD2 sgRNA CRISPR Lentivector (Human) (Target 3)
K1748904	ABM	1.0 ug DNA	EUR 184.8

Ptchd2 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K3185202	ABM	1.0 ug DNA	EUR 184.8

Ptchd2 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K3185203	ABM	1.0 ug DNA	EUR 184.8

Ptchd2 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K3185204	ABM	1.0 ug DNA	EUR 184.8

Mouse Patched domain- containing protein 2, Ptchd2 ELISA KIT
ELI-43078m	Lifescience Market	96 Tests	EUR 1038

Human Patched domain- containing protein 2, PTCHD2 ELISA KIT
ELI-44851h	Lifescience Market	96 Tests	EUR 988.8

PTCHD2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K1748905	ABM	3 x 1.0 ug	EUR 451.2

Ptchd2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K3185205	ABM	3 x 1.0 ug	EUR 451.2

PTCHD2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K1748906	ABM	1.0 ug DNA	EUR 200.4

PTCHD2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K1748907	ABM	1.0 ug DNA	EUR 200.4

PTCHD2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K1748908	ABM	1.0 ug DNA	EUR 200.4

Ptchd2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K3185206	ABM	1.0 ug DNA	EUR 200.4

Ptchd2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K3185207	ABM	1.0 ug DNA	EUR 200.4

Ptchd2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K3185208	ABM	1.0 ug DNA	EUR 200.4

PTCH1 Peptide
43-308P	ProSci	0.1 mg	EUR 405.6

PTCH Peptide
46-245P	ProSci	0.1 mg	EUR 405.6
Description: (CT) PTCH Peptide

PTCH Peptide
46-246P	ProSci	0.1 mg	EUR 405.6
Description: (IN) PTCH Peptide

PTCH1 Blocking Peptide
33R-9121	Fitzgerald	100 ug	EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PTCH1 antibody, catalog no. 70R-6354

PTCH2 Blocking Peptide
33R-4790	Fitzgerald	100 ug	EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PTCH2 antibody, catalog no. 70R-6356

PTCHD1 siRNA
20-abx930255	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

PTCHD1 siRNA
20-abx930256	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

PTCHD3 siRNA
20-abx930258	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

PTCHD3 siRNA
20-abx930259	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

PTCHD4 siRNA
20-abx930260	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

PTCHD4 siRNA
20-abx930261	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

PTCD2 Peptide
43-220P	ProSci	0.1 mg	EUR 405.6

PTCD2 Peptide
43-224P	ProSci	0.1 mg	EUR 405.6

PTCHD3 Antibody
R34501-100UG	NSJ Bioreagents	100 ug	EUR 339.15
Description: Additional name(s) for this target protein: Patched domain containing 3

PTCHD1 Antibody
R33444-100UG	NSJ Bioreagents	100 ug	EUR 339.15
Description: Additional name(s) for this target protein: Patched domain containing 1

Ptchd1 ORF Vector (Rat) (pORF)
ORF074258	ABM	1.0 ug DNA	EUR 607.2

PTCHD1 cloning plasmid
CSB-CL839383HU-10ug	Cusabio	10ug	EUR 921.6
Description: A cloning plasmid for the PTCHD1 gene.

PTCHD3 cloning plasmid
CSB-CL668587HU-10ug	Cusabio	10ug	EUR 568.8
Description: A cloning plasmid for the PTCHD3 gene.

PTCHD1 ORF Vector (Human) (pORF)
ORF014194	ABM	1.0 ug DNA	EUR 424.8

PTCHD3 ORF Vector (Human) (pORF)
ORF014195	ABM	1.0 ug DNA	EUR 424.8

PTCHD4 ORF Vector (Human) (pORF)
ORF028513	ABM	1.0 ug DNA	Ask for price

Ptchd1 ORF Vector (Mouse) (pORF)
ORF055151	ABM	1.0 ug DNA	EUR 607.2

Ptchd3 ORF Vector (Mouse) (pORF)
ORF055153	ABM	1.0 ug DNA	EUR 607.2

Ptchd1 3'UTR GFP Stable Cell Line
TU167222	ABM	1.0 ml	Ask for price

Ptchd3 3'UTR GFP Stable Cell Line
TU167224	ABM	1.0 ml	Ask for price

PTCHD1 3'UTR GFP Stable Cell Line
TU069131	ABM	1.0 ml	EUR 5540.4

PTCHD3 3'UTR GFP Stable Cell Line
TU069133	ABM	1.0 ml	EUR 1672.8

Ptchd1 3'UTR GFP Stable Cell Line
TU267013	ABM	1.0 ml	Ask for price

Ptchd3 3'UTR GFP Stable Cell Line
TU267014	ABM	1.0 ml	Ask for price

Human PTCHD1 shRNA Plasmid
20-abx965253	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

Mouse PTCHD1 shRNA Plasmid
20-abx980711	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

Mouse PTCHD4 shRNA Plasmid
20-abx984190	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

Mouse PTCHD3 shRNA Plasmid
20-abx978291	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

Human PTCHD3 shRNA Plasmid
20-abx967609	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

Human PTCHD4 shRNA Plasmid
20-abx968324	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

PTCHD1 Protein Vector (Rat) (pPM-C-HA)
PV297032	ABM	500 ng	EUR 1399.2

PTCHD1 Protein Vector (Rat) (pPB-C-His)
PV297030	ABM	500 ng	EUR 1399.2

PTCHD1 Protein Vector (Rat) (pPB-N-His)
PV297031	ABM	500 ng	EUR 1399.2

PTCHD1 Protein Vector (Rat) (pPM-C-His)
PV297033	ABM	500 ng	EUR 1399.2

PTCHD1 Protein Vector (Human) (pPM-C-HA)
PV056775	ABM	500 ng	EUR 577.2

PTCHD3 Protein Vector (Human) (pPM-C-HA)
PV056779	ABM	500 ng	EUR 577.2

PTCHD4 Protein Vector (Human) (pPM-C-HA)
PV114052	ABM	500 ng	Ask for price

PTCHD1 Protein Vector (Mouse) (pPM-C-HA)
PV220604	ABM	500 ng	EUR 1278

PTCHD3 Protein Vector (Mouse) (pPM-C-HA)
PV220612	ABM	500 ng	EUR 1278

Polyclonal PTCHD3 Antibody (C-term)
APR03561G	Leading Biology	0.1ml	EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTCHD3 (C-term). This antibody is tested and proven to work in the following applications:

PTCHD1 Protein Vector (Human) (pPB-C-His)
PV056773	ABM	500 ng	EUR 577.2

PTCHD1 Protein Vector (Human) (pPB-N-His)
PV056774	ABM	500 ng	EUR 577.2

PTCHD1 Protein Vector (Human) (pPM-C-His)
PV056776	ABM	500 ng	EUR 577.2

PTCHD3 Protein Vector (Human) (pPB-C-His)
PV056777	ABM	500 ng	EUR 577.2

PTCHD3 Protein Vector (Human) (pPB-N-His)
PV056778	ABM	500 ng	EUR 577.2

PTCHD3 Protein Vector (Human) (pPM-C-His)
PV056780	ABM	500 ng	EUR 577.2

PTCHD4 Protein Vector (Human) (pPB-C-His)
PV114050	ABM	500 ng	Ask for price

PTCHD4 Protein Vector (Human) (pPB-N-His)
PV114051	ABM	500 ng	Ask for price

PTCHD4 Protein Vector (Human) (pPM-C-His)
PV114053	ABM	500 ng	Ask for price

PTCHD1 Protein Vector (Mouse) (pPB-C-His)
PV220602	ABM	500 ng	EUR 1278

PTCHD1 Protein Vector (Mouse) (pPB-N-His)
PV220603	ABM	500 ng	EUR 1278

PTCHD1 Protein Vector (Mouse) (pPM-C-His)
PV220605	ABM	500 ng	EUR 1278

PTCHD3 Protein Vector (Mouse) (pPB-C-His)
PV220610	ABM	500 ng	EUR 1278

PTCHD3 Protein Vector (Mouse) (pPB-N-His)
PV220611	ABM	500 ng	EUR 1278

PTCHD3 Protein Vector (Mouse) (pPM-C-His)
PV220613	ABM	500 ng	EUR 1278

Ptchd1 3'UTR Luciferase Stable Cell Line
TU117222	ABM	1.0 ml	Ask for price

Ptchd3 3'UTR Luciferase Stable Cell Line
TU117224	ABM	1.0 ml	Ask for price

PTCHD1 3'UTR Luciferase Stable Cell Line
TU019131	ABM	1.0 ml	EUR 5540.4

PTCHD3 3'UTR Luciferase Stable Cell Line
TU019133	ABM	1.0 ml	EUR 1672.8

Ptchd1 3'UTR Luciferase Stable Cell Line
TU217013	ABM	1.0 ml	Ask for price

Ptchd3 3'UTR Luciferase Stable Cell Line
TU217014	ABM	1.0 ml	Ask for price

Ptchd1 sgRNA CRISPR Lentivector set (Rat)
K6195001	ABM	3 x 1.0 ug	EUR 406.8

PTCHD1 sgRNA CRISPR Lentivector set (Human)
K1748801	ABM	3 x 1.0 ug	EUR 406.8

PTCHD3 sgRNA CRISPR Lentivector set (Human)
K1749001	ABM	3 x 1.0 ug	EUR 406.8

Ptchd1 sgRNA CRISPR Lentivector set (Mouse)
K3867201	ABM	3 x 1.0 ug	EUR 406.8

Ptchd3 sgRNA CRISPR Lentivector set (Mouse)
K3246401	ABM	3 x 1.0 ug	EUR 406.8

Ptchd1 sgRNA CRISPR Lentivector (Rat) (Target 1)
K6195002	ABM	1.0 ug DNA	EUR 184.8

Ptchd1 sgRNA CRISPR Lentivector (Rat) (Target 2)
K6195003	ABM	1.0 ug DNA	EUR 184.8

Ptchd1 sgRNA CRISPR Lentivector (Rat) (Target 3)
K6195004	ABM	1.0 ug DNA	EUR 184.8

PTCHD1 sgRNA CRISPR Lentivector (Human) (Target 1)
K1748802	ABM	1.0 ug DNA	EUR 184.8

PTCHD1 sgRNA CRISPR Lentivector (Human) (Target 2)
K1748803	ABM	1.0 ug DNA	EUR 184.8

PTCHD1 sgRNA CRISPR Lentivector (Human) (Target 3)
K1748804	ABM	1.0 ug DNA	EUR 184.8

PTCHD3 sgRNA CRISPR Lentivector (Human) (Target 1)
K1749002	ABM	1.0 ug DNA	EUR 184.8

PTCHD3 sgRNA CRISPR Lentivector (Human) (Target 2)
K1749003	ABM	1.0 ug DNA	EUR 184.8

PTCHD3 sgRNA CRISPR Lentivector (Human) (Target 3)
K1749004	ABM	1.0 ug DNA	EUR 184.8

Ptchd1 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K3867202	ABM	1.0 ug DNA	EUR 184.8

Ptchd1 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K3867203	ABM	1.0 ug DNA	EUR 184.8

Ptchd1 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K3867204	ABM	1.0 ug DNA	EUR 184.8

Ptchd3 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K3246402	ABM	1.0 ug DNA	EUR 184.8

Ptchd3 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K3246403	ABM	1.0 ug DNA	EUR 184.8

Ptchd3 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K3246404	ABM	1.0 ug DNA	EUR 184.8

Polyclonal PTCHD1 Antibody (internal region)
APR13016G	Leading Biology	0.1 mg	EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PTCHD1 (internal region). This antibody is tested and proven to work in the following applications:

Polyclonal PTCHD3 Antibody (internal region)
APG00729G	Leading Biology	0.1mg	EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PTCHD3 (internal region). This antibody is tested and proven to work in the following applications:

Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
K6195005	ABM	3 x 1.0 ug	EUR 451.2

PTCHD4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
LV773435	ABM	1.0 ug DNA	EUR 1104

PTCHD4 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)
LV773439	ABM	1.0 ug DNA	EUR 1104

PTCHD1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K1748805	ABM	3 x 1.0 ug	EUR 451.2

PTCHD3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
K1749005	ABM	3 x 1.0 ug	EUR 451.2

Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K3867205	ABM	3 x 1.0 ug	EUR 451.2

Ptchd3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
K3246405	ABM	3 x 1.0 ug	EUR 451.2

Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
K6195006	ABM	1.0 ug DNA	EUR 200.4

Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
K6195007	ABM	1.0 ug DNA	EUR 200.4

Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
K6195008	ABM	1.0 ug DNA	EUR 200.4

PTCHD4 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)
LV773440	ABM	1.0 ug DNA	EUR 1104

Human Patched domain- containing protein 1, PTCHD1 ELISA KIT
ELI-37910h	Lifescience Market	96 Tests	EUR 988.8

Mouse Patched domain- containing protein 1, Ptchd1 ELISA KIT
ELI-30411m	Lifescience Market	96 Tests	EUR 1038

Human Patched domain- containing protein 3, PTCHD3 ELISA KIT
ELI-30412h	Lifescience Market	96 Tests	EUR 988.8

Mouse Patched domain- containing protein 3, Ptchd3 ELISA KIT
ELI-15541m	Lifescience Market	96 Tests	EUR 1038

TKD Peptide (Hsp70 Peptide) (Hsp70 Peptide)
SIH-118A	Stressmarq	1 mg	EUR 374.4
Description: The substance TKD Peptide (Hsp70 Peptide) is a hsp70 peptide. It is synthetically produced and has a purity of >98%. The pure substance is solid which is In aqueous solution.

Patched Domain-Containing Protein 3 (PTCHD3) Antibody
abx026245-400ul	Abbexa	400 ul	EUR 627.6

Patched Domain-Containing Protein 3 (PTCHD3) Antibody
abx026245-80l	Abbexa	80 µl	EUR 343.2

Patched Domain-Containing Protein 1 (PTCHD1) Antibody
abx431630-200ul	Abbexa	200 ul	EUR 460.8

Patched Domain-Containing Protein 3 (PTCHD3) Antibody
abx433196-200ul	Abbexa	200 ul	EUR 460.8

PTCHD1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K1748806	ABM	1.0 ug DNA	EUR 200.4

PTCHD1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K1748807	ABM	1.0 ug DNA	EUR 200.4

PTCHD1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K1748808	ABM	1.0 ug DNA	EUR 200.4

PTCHD3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K1749006	ABM	1.0 ug DNA	EUR 200.4

PTCHD3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
K1749007	ABM	1.0 ug DNA	EUR 200.4

PTCHD3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
K1749008	ABM	1.0 ug DNA	EUR 200.4

Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K3867206	ABM	1.0 ug DNA	EUR 200.4

Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K3867207	ABM	1.0 ug DNA	EUR 200.4

Ptchd1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K3867208	ABM	1.0 ug DNA	EUR 200.4

Ptchd3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
K3246406	ABM	1.0 ug DNA	EUR 200.4

Ptchd3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)
K3246407	ABM	1.0 ug DNA	EUR 200.4

Ptchd3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
K3246408	ABM	1.0 ug DNA	EUR 200.4

TKD Peptide (Hsp70 Peptide): FITC (Hsp70 Peptide)
SIH-119A	Stressmarq	1 mg	EUR 430.8
Description: The substance TKD Peptide (Hsp70 Peptide): FITC is a hsp70 peptide. It is synthetically produced and has a purity of >98%. The pure substance is solid which is In aqueous solution.

PTCHD4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
LV773436	ABM	1.0 ug DNA	EUR 1104

PTCHD4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
LV773437	ABM	1.0 ug DNA	EUR 1173.6

PTCHD4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
LV773438	ABM	1.0 ug DNA	EUR 1173.6

TKD Peptide (Hsp70 Peptide)
abx076809-1mg	Abbexa	1 mg	EUR 594

Rat Peptide YY (PYY) Peptide
20-abx068453	Abbexa	EUR 744.00 EUR 326.40 EUR 2230.80 EUR 878.40 EUR 543.60	100 ug 10 ug 1 mg 200 ug 50 ug

Human Connecting Peptide (C-Peptide) Peptide
abx670072-05mg	Abbexa	0.5 mg	EUR 678

Human Peptide YY (PYY) Peptide
20-abx068451	Abbexa	EUR 693.60 EUR 309.60 EUR 2013.60 EUR 811.20 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

Mouse Peptide YY (PYY) Peptide
20-abx068452	Abbexa	EUR 710.40 EUR 309.60 EUR 2131.20 EUR 844.80 EUR 526.80	100 ug 10 ug 1 mg 200 ug 50 ug

TKD Peptide (Hsp70 Peptide) (FITC)
abx076810-1mg	Abbexa	1 mg	EUR 678

Rat Connecting Peptide (C-Peptide) Peptide (OVA)
20-abx651058	Abbexa	EUR 510.00 EUR 276.00 EUR 1378.80 EUR 594.00 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Dog Peptide YY (PYY) Peptide (OVA)
20-abx651198	Abbexa	EUR 427.20 EUR 260.40 EUR 1178.40 EUR 526.80 EUR 343.20	100 ug 10 ug 1 mg 200 ug 50 ug

Pig Peptide YY (PYY) Peptide (OVA)
20-abx651200	Abbexa	EUR 427.20 EUR 260.40 EUR 1178.40 EUR 526.80 EUR 343.20	100 ug 10 ug 1 mg 200 ug 50 ug

Even though we only observed the PP association with anxiety and age with NPY and PP in men, suggesting the possibility of the effect of sex hormones on the NPY system. However, an increase in anxiety scores does not lead to significant changes in NPY.