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A clinically-relevant polymorphism in the Na +/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position

A clinically-relevant polymorphism in the Na +/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position
Posted by Anna

Conventionally, most of the substitution of amino acids in important protein positions is expected to eliminate the function. However, in some soluble globular proteins, we identify non-conservation positions that various substitutions produce progressive functional changes; We consider “Rheostats” of this evolution. Here, we report a strong rheostat position in integral membrane protein, NA + / Taurocholate Cotransporting Polypeptide (NTCP), at the location of the polymorphism that is pharmacologically relevant (S267F). Functional studies are carried out for all 20 substitutions (“S267x”) with three substrates (taurocholate, estrone-3-sulfate and rosuvastatin).

The S267X set shows a strong reosatic effect on overall transportation, and individual replacement shows the effects vary in transportation kinetics (KM and Vmax) and substrate specificity. To assess protein stability, we measure surface expression and use the Rosetta software suite to model the structure and change of S267X stability. Despite being buried near the substrate binding site, the S267X substitution is easily accommodated in the NTCP structure model. In various changes, calculated stability correlates with differences in surface expression, but no parameters correlated with changed transport. Thus, the substitution in the position of Rheostat 267 has a broad effect on the phenotype of this integral membrane protein. We then propose that the polymorphic position in other proteins might be the location of the position of Rheostat.

The study mechanism of abnormal accumulation and deposition of amyloid islet polypeptides with cold ionization mass spectrometry

Abnormal accumulation and deposition of polypeptide pullet amyloid (IAPP) is an important cause of type-2 type diabetes mellitus (T2DM). General anti-amyloid strategies employ inhibitors to prevent the formation of oligomers and cytotoxicity caused by them, thereby reducing the production of amyloid fibers. Therefore, the real characterization of the Oligomers formed at the initial stage of aggregation is very important to understand the IAPP structure and the development of T2DM drugs.

For the first time, in this study, the original Ionization Spectrometry Technology of the original spray (CSI-MS) was hired to characterize the oligomers. It was found that CSI was more suitable for determining this unstable species compared to traditional MS ESI. Ion strength, organic solvents and pH all have an effect on the characterization of oligomers and stability of protein conformation. MS / MS experiment shows that odd charging dimer ions consist mainly of two monomer products. In addition, the CSI-MS method for quick screening of IAPP-inhibitors was established and two most potential inhibitors (routine and quercitrin) were played from a series of flavonoids.

Then, the relationship between activities and mechanisms between flavonoids and IAPP is studied. The results showed that the 3-oh chain and sugar played a vital role and hydrogen bonds was the power of the main binding. We subsequently confirm that routine and quercitrin can effectively inhibit the formation of IAPP fibers by fluorescence and TEM experiments. This study provides new insights to analyze the IAPP structure and potential drug screening for T2DM.

Evaluation of chromatographic parameters in the chromatography of the amino acid supercritic liquid as a polar analyte model and expanded to the separation of polypeptides

Chromatographic parameters have been evaluated regarding amino acid acid supercritical chromatography as a model compound for polar substances and is subject to biochemical and biopharmaceutical interests. The inherent hydrofilisity requires the appropriate chromatographic conditions regarding the stationary phase and moves to obtain suitable solubility and peak performance. Ten different stationary phases in polarity and types of ligands including neutral and charged with investigated regarding selectivity, peak performance, and complementary orthogonality. Mobile phase compositions regarding solvents and types of buffer additives by varying hydrophobicity degrees of acid and base and substitution level in the case of basic amines. The addition of water to methanol solvents is then found is very important to get high peak performance. Some complementary selectivity can be obtained depending on the choice of column.

A clinically-relevant polymorphism in the Na +/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position
A clinically-relevant polymorphism in the Na +/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position

Variations of temperature and pressure are basically only influenced by retention without selectivity change. The appropriate conditions obtained for amino acids are then successfully applied to oligo and polypeptides allow the separation of 4 polypeptides and differ in just one of 39 amino acids, thus mimicing analysis of biotransformation reaction products. Utilization of water as a cellphone additive and sulfonate acid as a buffer agent can function as a generic methodology for polar compounds and charged like amino containing biomolecules.

Polypeptide nanoparticles with pegylated ph-sheddable for enhanced drug delivery

Microenvironment tumor variations provide tools for the construction of nanomedicina responsive stimulus to increase the efficacy of drug administration. Here, the assembly of polypeptide nanoparticles loaded by drugs (NPS) with modification of PH-Sheddable Poly (Ethylene Glycol) (PEG) is prepared to improve therapeutic efficiency. Poly (L-Lysine) and Poly (L-Glutamic Acid) are assembled themselves to make Polypeptide NPS with electrostatic interactions, followed by a firewell based on a syrading reaction. The size of the NP can be controlled by setting the molecular weight or polypeptide ratio.

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx177223
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx177224
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx177225
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx177226
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx177227
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx214359
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx324813
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx131920
  • EUR 376.80
  • EUR 944.40
  • EUR 493.20
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx002102
  • EUR 493.20
  • EUR 710.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Islet Amyloid Polypeptide (IAPP) Antibody

20-abx304190
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Pig Islet amyloid polypeptide ELISA kit

E07I0321-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Islet amyloid polypeptide ELISA kit

E07I0321-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Islet amyloid polypeptide ELISA kit

E07I0321-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Islet amyloid polypeptide ELISA kit

E08I0321-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Islet amyloid polypeptide ELISA kit

E08I0321-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Islet amyloid polypeptide ELISA kit

E08I0321-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Islet amyloid polypeptide ELISA kit

E02I0321-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Islet amyloid polypeptide ELISA kit

E02I0321-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Islet amyloid polypeptide ELISA kit

E02I0321-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Islet amyloid polypeptide ELISA kit

E06I0321-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Islet amyloid polypeptide ELISA kit

E06I0321-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Islet amyloid polypeptide ELISA kit

E06I0321-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Islet amyloid polypeptide ELISA kit

E03I0321-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Islet amyloid polypeptide ELISA kit

E03I0321-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Islet amyloid polypeptide ELISA kit

E03I0321-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Islet amyloid polypeptide ELISA kit

E01I0321-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Islet amyloid polypeptide ELISA kit

E01I0321-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Islet amyloid polypeptide ELISA kit

E01I0321-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Islet amyloid polypeptide Polyclonal Antibody

42558-100ul 100ul
EUR 399.6

Rat Islet Amyloid Polypeptide (IAPP) Peptide

20-abx654084
  • EUR 627.60
  • EUR 292.80
  • EUR 1796.40
  • EUR 727.20
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rabbit Islet amyloid polypeptide ELISA kit

E04I0321-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Islet amyloid polypeptide ELISA kit

E04I0321-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Islet amyloid polypeptide ELISA kit

E04I0321-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Islet amyloid polypeptide ELISA kit

E09I0321-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Islet amyloid polypeptide ELISA kit

E09I0321-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Islet amyloid polypeptide ELISA kit

E09I0321-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Islet Amyloid Polypeptide (IAPP) Antibody (HRP)

20-abx108436
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Islet Amyloid Polypeptide (IAPP) Antibody (HRP)

20-abx304191
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Islet Amyloid Polypeptide (IAPP) Antibody (FITC)

20-abx107015
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Islet Amyloid Polypeptide (IAPP) Peptide

20-abx654081
  • EUR 627.60
  • EUR 292.80
  • EUR 1796.40
  • EUR 727.20
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Islet Amyloid Polypeptide (IAPP) Peptide

20-abx654082
  • EUR 627.60
  • EUR 292.80
  • EUR 1796.40
  • EUR 727.20
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Islet Amyloid Polypeptide (IAPP) Antibody (FITC)

20-abx304192
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

BSA Conjugated Islet Amyloid Polypeptide (IAPP)

4-CPA812Hu11
  • EUR 276.98
  • EUR 196.80
  • EUR 708.67
  • EUR 316.22
  • EUR 512.45
  • EUR 260.40
  • EUR 1591.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Islet Amyloid Polypeptide expressed in: Protein conjugation

OVA Conjugated Islet Amyloid Polypeptide (IAPP)

4-CPA812Hu21
  • EUR 276.98
  • EUR 196.80
  • EUR 708.67
  • EUR 316.22
  • EUR 512.45
  • EUR 260.40
  • EUR 1591.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Islet Amyloid Polypeptide expressed in: Protein conjugation

OVA conjugated Islet Amyloid Polypeptide (IAPP)

4-CPA812Hu22
  • EUR 496.32
  • EUR 256.80
  • EUR 1531.20
  • EUR 590.40
  • EUR 1060.80
  • EUR 408.00
  • EUR 3648.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Islet Amyloid Polypeptide expressed in: Protein conjugation

KLH Conjugated Islet Amyloid Polypeptide (IAPP)

4-CPA812Hu33
  • EUR 301.70
  • EUR 204.00
  • EUR 801.41
  • EUR 347.14
  • EUR 574.27
  • EUR 277.20
  • EUR 1823.52
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Islet Amyloid Polypeptide expressed in: Protein conjugation

BSA Conjugated Islet Amyloid Polypeptide (IAPP)

4-CPA812Mu11
  • EUR 276.98
  • EUR 196.80
  • EUR 708.67
  • EUR 316.22
  • EUR 512.45
  • EUR 260.40
  • EUR 1591.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Islet Amyloid Polypeptide expressed in: Protein conjugation

OVA Conjugated Islet Amyloid Polypeptide (IAPP)

4-CPA812Mu21
  • EUR 276.98
  • EUR 196.80
  • EUR 708.67
  • EUR 316.22
  • EUR 512.45
  • EUR 260.40
  • EUR 1591.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Islet Amyloid Polypeptide expressed in: Protein conjugation

BSA Conjugated Islet Amyloid Polypeptide (IAPP)

4-CPA812Ra11
  • EUR 276.98
  • EUR 196.80
  • EUR 708.67
  • EUR 316.22
  • EUR 512.45
  • EUR 260.40
  • EUR 1591.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Islet Amyloid Polypeptide expressed in: Protein conjugation

OVA Conjugated Islet Amyloid Polypeptide (IAPP)

4-CPA812Ra21
  • EUR 276.98
  • EUR 196.80
  • EUR 708.67
  • EUR 316.22
  • EUR 512.45
  • EUR 260.40
  • EUR 1591.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Islet Amyloid Polypeptide expressed in: Protein conjugation

Rat Islet Amyloid Polypeptide (IAPP) CLIA Kit

20-abx490251
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

ELISA kit for Rat Islet amyloid polypeptide

EK2274 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat Islet amyloid polypeptide in samples from serum, plasma, tissue homogenates and other biological fluids.

Islet Amyloid Polypeptide (IAPP) Antibody (Biotin)

20-abx105597
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Islet Amyloid Polypeptide (IAPP) Antibody (Biotin)

20-abx304193
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx256352-96tests 96 tests
EUR 904.8

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

20-abx155661
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Pig Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx361955-96tests 96 tests
EUR 990

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Ra-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Rat Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Ra-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Rat Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Ra-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Rat Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Ra-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Rat Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

4-CEA812Ra
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Rat Islet Amyloid Polypeptide (IAPP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Cow Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx514065-96tests 96 tests
EUR 1093.2

Dog Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx514066-96tests 96 tests
EUR 1093.2

Pig Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx514069-96tests 96 tests
EUR 990

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx575836-96tests 96 tests
EUR 904.8

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

DLR-IAPP-Ra-48T 48T
EUR 609.6
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Islet Amyloid Polypeptide (IAPP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

DLR-IAPP-Ra-96T 96T
EUR 793.2
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Islet Amyloid Polypeptide (IAPP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Iapp(Islet amyloid polypeptide) ELISA Kit

ER0374 96T
EUR 681.12
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 46.9pg/ml

Rat Iapp/ Islet amyloid polypeptide ELISA Kit

E0482Ra 1 Kit
EUR 685.2

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

RDR-IAPP-Ra-48Tests 48 Tests
EUR 640.8

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

RDR-IAPP-Ra-96Tests 96 Tests
EUR 890.4

Rat Islet Amyloid Polypeptide ELISA Kit (IAPP)

RK03730 96 Tests
EUR 625.2

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Ra-48Tests 48 Tests
EUR 613.2

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Ra-96Tests 96 Tests
EUR 850.8

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Ra-48T 48T
EUR 443.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Ra-96T 96T
EUR 633.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat Islet amyloid polypeptide,IAPP ELISA Kit

YLA1190RA-48T 48T
EUR 465

Rat Islet amyloid polypeptide,IAPP ELISA Kit

YLA1190RA-96T 96T
EUR 600

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

RDR-IAPP-Ra-48T 48T
EUR 465.47
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Rat Islet Amyloid Polypeptide (IAPP) ELISA Kit

RDR-IAPP-Ra-96T 96T
EUR 664.97
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Islet Amyloid Polypeptide (IAPP) CLIA Kit

abx195533-96tests 96 tests
EUR 990

Human Islet Amyloid Polypeptide (IAPP) CLIA Kit

20-abx490249
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Islet Amyloid Polypeptide (IAPP) CLIA Kit

20-abx490250
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

ELISA kit for Mouse Islet amyloid polypeptide

EK2273 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Islet amyloid polypeptide in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Human Islet amyloid polypeptide

EK2275 96 tests
EUR 542.4
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Islet amyloid polypeptide in samples from serum, plasma, tissue homogenates and other biological fluids.

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

20-abx151890
  • EUR 7970.40
  • EUR 4250.40
  • EUR 990.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx253521-96tests 96 tests
EUR 848.4

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

20-abx154169
  • EUR 7970.40
  • EUR 4250.40
  • EUR 990.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human islet amyloid polypeptide,IAPP ELISA Kit

201-12-0003 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

4-CEA812Hu
  • EUR 5188.80
  • EUR 2739.60
  • EUR 703.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Islet Amyloid Polypeptide (IAPP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Mu-10x96wellstestplate 10x96-wells test plate
EUR 5269.39
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Mu-1x48wellstestplate 1x48-wells test plate
EUR 539.12
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Mu-1x96wellstestplate 1x96-wells test plate
EUR 718.75
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Mu-5x96wellstestplate 5x96-wells test plate
EUR 2874.38
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

4-CEA812Mu
  • EUR 5330.40
  • EUR 2815.20
  • EUR 718.80
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Mouse Islet Amyloid Polypeptide (IAPP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Hu-10x96wellstestplate 10x96-wells test plate
EUR 5128.02
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Human Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Hu-1x48wellstestplate 1x48-wells test plate
EUR 527.48
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Human Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Hu-1x96wellstestplate 1x96-wells test plate
EUR 702.12
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Human Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

CEA812Hu-5x96wellstestplate 5x96-wells test plate
EUR 2799.54
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Human Islet Amyloid Polypeptide (IAPP) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx051311-96tests 96 tests
EUR 904.8

Rat Islet Amyloid Polypeptide (IAPP) Peptide (BSA)

20-abx651117
  • EUR 376.80
  • EUR 243.60
  • EUR 978.00
  • EUR 427.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Islet Amyloid Polypeptide (IAPP) Peptide (OVA)

20-abx651118
  • EUR 376.80
  • EUR 243.60
  • EUR 978.00
  • EUR 427.20
  • EUR 309.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx514067-96tests 96 tests
EUR 848.4

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx576134-96tests 96 tests
EUR 943.2

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

abx353241-96tests 96 tests
EUR 943.2

Human islet amyloid polypeptide, IAPP ELISA Kit

CSB-E09624h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human islet amyloid polypeptide, IAPP in samples from serum, plasma, urine. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human islet amyloid polypeptide, IAPP ELISA Kit

1-CSB-E09624h
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human islet amyloid polypeptide, IAPP in samples from serum, plasma, urine. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human islet amyloid polypeptide,IAPP ELISA Kit

CN-04260H1 96T
EUR 529.2

Human islet amyloid polypeptide,IAPP ELISA Kit

CN-04260H2 48T
EUR 349.2

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

DLR-IAPP-Hu-48T 48T
EUR 574.8
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Islet Amyloid Polypeptide (IAPP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

DLR-IAPP-Hu-96T 96T
EUR 745.2
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Islet Amyloid Polypeptide (IAPP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

DLR-IAPP-Mu-48T 48T
EUR 586.8
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Islet Amyloid Polypeptide (IAPP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

DLR-IAPP-Mu-96T 96T
EUR 762
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Islet Amyloid Polypeptide (IAPP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Iapp(Islet amyloid polypeptide) ELISA Kit

EM1866 96T
EUR 681.12
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 4.688pg/ml

Guinea pig Islet amyloid polypeptide ELISA kit

E05I0321-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Islet amyloid polypeptide ELISA kit

E05I0321-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Islet amyloid polypeptide ELISA kit

E05I0321-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Islet amyloid polypeptide in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Iapp/ Islet amyloid polypeptide ELISA Kit

E0713Mo 1 Kit
EUR 685.2

Human islet amyloid polypeptide(IAPP)ELISA Kit

GA-E0050HM-48T 48T
EUR 346.8

Human islet amyloid polypeptide(IAPP)ELISA Kit

GA-E0050HM-96T 96T
EUR 559.2

Human Islet amyloid polypeptide, IAPP ELISA KIT

ELI-02741h 96 Tests
EUR 988.8

Mouse Islet amyloid polypeptide, Iapp ELISA KIT

ELI-02743m 96 Tests
EUR 1038

Human islet amyloid polypeptide, IAPP ELISA Kit

ELA-67017h 96 Tests
EUR 788.4

Human IAPP/ Islet amyloid polypeptide ELISA Kit

E1198Hu 1 Kit
EUR 644.4

Human IAPP(Islet amyloid polypeptide ) ELISA Kit

EH0553 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human Islet Amyloid Polypeptide ELISA Kit (IAPP)

RK01617 96 Tests
EUR 625.2

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

RDR-IAPP-Hu-48Tests 48 Tests
EUR 600

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

RDR-IAPP-Hu-96Tests 96 Tests
EUR 830.4

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

RDR-IAPP-Mu-48Tests 48 Tests
EUR 613.2

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

RDR-IAPP-Mu-96Tests 96 Tests
EUR 850.8

Mouse Islet Amyloid Polypeptide ELISA Kit (IAPP)

RK02908 96 Tests
EUR 625.2

Human islet amyloid polypeptide(IAPP)ELISA Kit

QY-E00520 96T
EUR 433.2

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Hu-48Tests 48 Tests
EUR 573.6

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Hu-96Tests 96 Tests
EUR 794.4

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Mu-48Tests 48 Tests
EUR 586.8

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Mu-96Tests 96 Tests
EUR 812.4

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Hu-48T 48T
EUR 411.8
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Hu-96T 96T
EUR 588.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Mu-48T 48T
EUR 422.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Mouse Islet Amyloid Polypeptide (IAPP) ELISA Kit

RD-IAPP-Mu-96T 96T
EUR 603.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Sheep Islet amyloid polypeptide,IAPP ELISA Kit

YLA0074SH-48T 48T
EUR 540

Sheep Islet amyloid polypeptide,IAPP ELISA Kit

YLA0074SH-96T 96T
EUR 645

Mouse Islet amyloid polypeptide,IAPP ELISA Kit

YLA1332MO-48T 48T
EUR 465

Mouse Islet amyloid polypeptide,IAPP ELISA Kit

YLA1332MO-96T 96T
EUR 600

Human Islet amyloid polypeptide,IAPP ELISA Kit

YLA1490HU-48T 48T
EUR 435

PEG coating can be issued on tumor acid environments to reverse surface load and reduce NP size, which effectively increases cell absorption. In addition, the existence of reducing reagents (eg, glutathione) in cancer cells induces drugs (i.e., cisplatin) releases from polypeptide NPS and then produces cell toxicity. This reported method highlights the technique of transformed polypeptide drug operators, which provides promising ways to increase the efficacy of drug administration.

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