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[Effect of electroacupuncture on intestinal Toll-like receptor 4 and nuclear factor-kappa B in obese rats]

[Effect of electroacupuncture on intestinal Toll-like receptor 4 and nuclear factor-kappa B in obese rats]
Posted by Anna

Objective: To determine the effect of electroacupuncture (EA) on intestinal Toll-like receptor 4 (TLR4) and nuclear factor-kappa B (NF-kB) in obese mice, so as to explore the mechanism of action of acupuncture to lose weight.
Methods: A total of 50 male Wistar rats were randomly divided into control and model of the group. high-fat feed used to establish a mouse model of obesity, and after modeling, 24 rats were randomly divided into model group, TLR4 inhibitor group and EA group, with 8 rats in each group.

Mice in group EA by EA at “Guanyuan” (CV4), “Zhongwan” (CV12), “Zusanli” (ST36), and “Fenglong” (ST40), 10 minutes each time, three times a week, and they were in a group of inhibitors TLR4 were given intraperitoneal injection of TAK-242 three times a week; course of treatment was 8 weeks for both groups. weight and the body’s blood sugar was measured every two weeks. Co-immunoprecipitation was used to observe the interaction between TLR4 and NF-kB p65 in colon tissue; electrophoretic mobility shift test is used to measure the activity of NF-kB p65; Western blot was used to measure the expression of TLR4 protein, phosphorylated nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor alpha (p-IκBα), and NF-kB p65; Quantitative real-time PCR was used to measure mRNA expression of TLR4, NF-kB p65 and IκBα.


Results: Compared with the control group, the model group had significant increases in weight, blood glucose, and protein and mRNA expression of TLR4 and NF-kB p65 (P <0.01, P <0.05), as well as a significant increase in interaction between TLR4 and NF-kB p65 and NF-kB p65 activity (P <0.05, P <0.01). Compared with the model group, EA group had a significant reduction in body weight (P <0.05), both groups EA and TLR4 inhibitor group had a significant reduction in blood glucose, and protein and mRNA expression of TLR4, p-IκBα and NF -kB p65 (P <0.05, P <0.01), as well as a significant reduction in the activity of NF-kB p65 (P <0.01).
Conclusion: EA can effectively regulate TLR4 intestine, inhibits the interaction between TLR4 and NF-kB p65, and reduce the activity of NF-kB p65, which may be a potential mechanism of EA in reducing weight and blood glucose in obese mice.

[Effect of electroacupuncture on intestinal Toll-like receptor 4 and nuclear factor-kappa B in obese rats]
[Effect of electroacupuncture on intestinal Toll-like receptor 4 and nuclear factor-kappa B in obese rats]

Orobol, derivatives of genistein, inhibits heat-killed Propionibacterium acnes-induced inflammation in HaCaT keratinocyte

Acne is a chronic skin disease that usually occurs in teens and twenties, and symptoms vary according to the age, sex, diet, and lifestyle. Acne is characterized by hyperproliferation of keratinocytes in the epidermis, excess sebum, the growth of Propionibacterium acnes, and P. acnes induced skin inflammation. Interleukin (IL) -1α and IL-6 were dominant in inflammatory lesions of acne vulgaris. This cytokine induces an inflammatory reaction of the skin in the presence of a pathogen or pressure.

Human Phospho inhibitory subunit of NF kappaB alpha(pIKBalpha) ELISA Kit

NSL0362Hu 96 wells
EUR 468

Canine Phospho inhibitory subunit of NF kappaB alpha(pIKBalpha) ELISA Kit

NSL1195Ca 1290 wells
EUR 528

Bovine Phospho inhibitory subunit of NF kappaB alpha(pIKBalpha) ELISA Kit

NSL1168Bo 96 T
EUR 528

Rat IKBα(Inhibitory Subunit of NF-κBα) ELISA Kit

ER1084 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml

Rat inhibitory subunit of NF-κBα,IKBα ELISA Kit

SL0369Ra -
EUR 498

CLIA kit for Rat IKB? (Inhibitory Subunit of NF-?B?)

E-CL-R0363 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Rat IKB? (Inhibitory Subunit of NF-?B?) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Rat IKB? (Inhibitory Subunit of NF-?B?)

E-EL-R0525 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Rat IKB? (Inhibitory Subunit of NF-?B?) in samples from Serum, Plasma, Cell supernatant

Rat Inhibitory Subunit of NF-kB alpha (IKBa) CLIA Kit

abx197167-96tests 96 tests
EUR 990

Human inhibitory subunit of NF-?B?,IKB? ELISA Kit

201-12-0683 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Rat Inhibitory Subunit Of NF Kappa B Beta(IkBb)ELISA kit

QY-E10272 96T
EUR 433.2

Rat Inhibitory Subunit of NF-KBA Chemiluminescent Immunoassay Kit

IRTIKBAKTC each
EUR 545
Description: Rat Inhibitory Subunit of NF-KBA Chemiluminescent Immunoassay Kit

Rat Inhibitory Subunit Of NF Kappa B Alpha(IkBa)ELISA kit

QY-E10273 96T
EUR 433.2

Human inhibitory subunit of NF-κBα(IKBα)ELISA Kit

GA-E0699HM-48T 48T
EUR 346.8

Human inhibitory subunit of NF-κBα(IKBα)ELISA Kit

GA-E0699HM-96T 96T
EUR 559.2

Mouse inhibitory subunit of NF-κBα(IKBα)ELISA Kit

GA-E0191MS-48T 48T
EUR 403.2

Mouse inhibitory subunit of NF-κBα(IKBα)ELISA Kit

GA-E0191MS-96T 96T
EUR 640.8

Human inhibitory subunit of NF-κBα(IKBα)ELISA Kit

QY-E03141 96T
EUR 433.2

Human inhibitory subunit of NF-κBα,IKBα ELISA Kit

YLA2357HU-48T 48T
EUR 435

Human inhibitory subunit of NF-κBα,IKBα ELISA Kit

YLA2357HU-96T 96T
EUR 562.5

Mouse inhibitory subunit of NF-κBα,IKBα ELISA Kit

YLA0368MO-48T 48T
EUR 465

Mouse inhibitory subunit of NF-κBα,IKBα ELISA Kit

YLA0368MO-96T 96T
EUR 600

Human Inhibitory Subunit Of NF Kappa B Alpha ELISA Kit

IHUIKBAKT each
EUR 700
Description: Human Inhibitory Subunit Of NF Kappa B Alpha ELISA Kit

Mouse Inhibitory Subunit Of NF Kappa B Alpha ELISA Kit

IMSIKBAKT each
EUR 718
Description: Mouse Inhibitory Subunit Of NF Kappa B Alpha ELISA Kit

Inhibitory Subunit of NF Kappa B Beta (IkBb) Antibody

20-abx103917
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Zeta (IkBz) Antibody

20-abx103918
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Zeta (IkBz) Antibody

20-abx103919
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Beta (IkBb) Antibody

20-abx128815
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Alpha (IkBa) Antibody

20-abx104016
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Delta (IkBd) Antibody

20-abx104017
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Antibody

20-abx172896
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Antibody

20-abx176941
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit Of NF Kappa B Alpha (IkBa) Antibody

20-abx176942
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Inhibitory Subunit of NF Kappa B Delta (IkBd) Antibody

20-abx129839
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Inhibitory Subunit of NF Kappa B Alpha (IκBa) CLIA Kit

abx197166-96tests 96 tests
EUR 990

Mouse Inhibitory Subunit Of NF Kappa B Beta(IkBb)ELISA kit

QY-E20793 96T
EUR 433.2

Human Inhibitory Subunit Of NF Kappa B Beta(IkBb)ELISA Kit

QY-E03140 96T
EUR 433.2

Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz) ELISA Kit

EKN53101-48T 48T
EUR 355.6

Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz) ELISA Kit

EKN53101-5x96T 5x96T
EUR 2413

Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz) ELISA Kit

EKN53101-96T 96T
EUR 508

Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz) ELISA Kit

EKU11990-48T 48T
EUR 571.55

Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz) ELISA Kit

EKU11990-5x96T 5x96T
EUR 3878.38

Mouse Inhibitory Subunit Of NF Kappa B Zeta (IkBz) ELISA Kit

EKU11990-96T 96T
EUR 816.5

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

4-SEB848Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Mu-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Mu-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Mu-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

SEB848Mu-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

4-SEB848Mu
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Inhibitory Subunit Of NF Kappa B Alpha ELISA Kit (IkBa)

RK01651 96 Tests
EUR 625.2

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Hu-48Tests 48 Tests
EUR 626.4

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Hu-96Tests 96 Tests
EUR 868.8

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Mu-48Tests 48 Tests
EUR 640.8

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Mu-96Tests 96 Tests
EUR 890.4

Mouse Inhibitory Subunit Of NF Kappa B Alpha(IkBa)ELISA kit

QY-E20792 96T
EUR 433.2

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Hu-48Tests 48 Tests
EUR 600

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Hu-96Tests 96 Tests
EUR 830.4

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Mu-48Tests 48 Tests
EUR 613.2

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Mu-96Tests 96 Tests
EUR 850.8

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Hu-48T 48T
EUR 453.92
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Hu-96T 96T
EUR 648.38
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Mu-48T 48T
EUR 465.47
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RDR-IkBa-Mu-96T 96T
EUR 664.97
Description: tissue homogenates, cell lysates and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DL-IkBa-Hu 96T
EUR 421
Description: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DL-IkBa-Mu 96T
EUR 432
Description: tissue homogenates, cell lysates or other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Hu 96T
EUR 443
Description: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

DLR-IkBa-Mu 96T
EUR 454
Description: tissue homogenates, cell lysates or other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Hu-48T 48T
EUR 432.3
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Hu-96T 96T
EUR 617.5
Description: tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Mu-48T 48T
EUR 443.3
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

RD-IkBa-Mu-96T 96T
EUR 633.3
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse IkBα (Inhibitory Subunit of NF Kappa B Alpha) ELISA Kit

EKE61735-5x96T 5x96T
EUR 3124.08

Mouse IkBα (Inhibitory Subunit of NF Kappa B Alpha) ELISA Kit

EKE61735-96T 96T
EUR 657.7

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKN52046-48T 48T
EUR 361.55

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKN52046-5x96T 5x96T
EUR 2453.38

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKN52046-96T 96T
EUR 516.5

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKU04945-48T 48T
EUR 527.66

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKU04945-5x96T 5x96T
EUR 3580.55

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKU04945-96T 96T
EUR 753.8

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKU04946-48T 48T
EUR 542.78

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKU04946-5x96T 5x96T
EUR 3683.15

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKU04946-96T 96T
EUR 775.4

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKU10935-48T 48T
EUR 581.35

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKU10935-5x96T 5x96T
EUR 3944.88

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKU10935-96T 96T
EUR 830.5

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKN46056-48T 48T
EUR 359.87

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKN46056-5x96T 5x96T
EUR 2441.98

Human Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKN46056-96T 96T
EUR 514.1

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKN46057-48T 48T
EUR 370.02

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKN46057-5x96T 5x96T
EUR 2510.85

Mouse Inhibitory Subunit Of NF Kappa B Alpha (IkBa) ELISA Kit

EKN46057-96T 96T
EUR 528.6

Mouse IkBa(Inhibitory Subunit Of NF Kappa B Alpha) ELISA Kit

ELK4340-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse IkBa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse IkBa. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse IkBa, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse IkBa in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse IkBa(Inhibitory Subunit Of NF Kappa B Alpha) ELISA Kit

ELK4340-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse IkBa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse IkBa. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse IkBa, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse IkBa in the samples is then determined by comparing the OD of the samples to the standard curve.

Human IkBa(Inhibitory Subunit Of NF Kappa B Alpha) ELISA Kit

ELK2219-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human IkBa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human IkBa. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human IkBa, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human IkBa in the samples is then determined by comparing the OD of the samples to the standard curve.

Human IkBa(Inhibitory Subunit Of NF Kappa B Alpha) ELISA Kit

ELK2219-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human IkBa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human IkBa. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human IkBa, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human IkBa in the samples is then determined by comparing the OD of the samples to the standard curve.

Inhibitory Subunit of NF Kappa B Epsilon (IkBe) Antibody

20-abx104115
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Inhibitory Subunit of NF Kappa B Epsilon (IkBe) Antibody

20-abx129779
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

4-RPC249Hu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Inhibitory Subunit Of NF Kappa B Zeta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

4-RPC249Mu01
  • EUR 642.55
  • EUR 295.20
  • EUR 2079.55
  • EUR 773.18
  • EUR 1426.37
  • EUR 505.20
  • EUR 5018.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Inhibitory Subunit Of NF Kappa B Zeta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

4-RPB849Hu01
  • EUR 588.79
  • EUR 280.80
  • EUR 1877.95
  • EUR 705.98
  • EUR 1291.97
  • EUR 469.20
  • EUR 4514.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Inhibitory Subunit Of NF Kappa B Beta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

4-RPB849Mu01
  • EUR 588.79
  • EUR 280.80
  • EUR 1877.95
  • EUR 705.98
  • EUR 1291.97
  • EUR 469.20
  • EUR 4514.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Inhibitory Subunit Of NF Kappa B Beta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

RPU42014-100ug 100ug
EUR 537.9

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

RPU42014-1mg 1mg
EUR 2380.3

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

RPU42014-50ug 50ug
EUR 431.2

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

RPU42017-100ug 100ug
EUR 542.3

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

RPU42017-1mg 1mg
EUR 2402.4

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

RPU42017-50ug 50ug
EUR 435.6

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

RPU42018-100ug 100ug
EUR 599.5

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

RPU42018-1mg 1mg
EUR 2653.3

Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz)

RPU42018-50ug 50ug
EUR 480.7

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

RPU52835-100ug 100ug
EUR 537.9

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

RPU52835-1mg 1mg
EUR 2380.3

Recombinant Inhibitory Subunit Of NF Kappa B Beta (IkBb)

RPU52835-50ug 50ug
EUR 431.2

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

4-RPE701Hu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Inhibitory Subunit Of NF Kappa B Delta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

4-RPE701Mu01
  • EUR 614.59
  • EUR 288.00
  • EUR 1974.72
  • EUR 738.24
  • EUR 1356.48
  • EUR 487.20
  • EUR 4756.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Inhibitory Subunit Of NF Kappa B Delta expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Alpha (IkBa)

4-RPB848Hu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Inhibitory Subunit Of NF Kappa B Alpha expressed in: E.coli

Recombinant Inhibitory Subunit Of NF Kappa B Alpha (IkBa)

RPU42013-100ug 100ug
EUR 530.2

Recombinant Inhibitory Subunit Of NF Kappa B Alpha (IkBa)

RPU42013-1mg 1mg
EUR 2347.8

Recombinant Inhibitory Subunit Of NF Kappa B Alpha (IkBa)

RPU42013-50ug 50ug
EUR 425.7

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

RPU42015-100ug 100ug
EUR 530.2

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

RPU42015-1mg 1mg
EUR 2347.8

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

RPU42015-50ug 50ug
EUR 425.7

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

RPU53981-100ug 100ug
EUR 566.5

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

RPU53981-1mg 1mg
EUR 2511.6

Recombinant Inhibitory Subunit Of NF Kappa B Delta (IkBd)

RPU53981-50ug 50ug
EUR 455.4

In addition, IL-1α accelerate the production of keratin 16, which is normally expressed in the skin is injured or distorted, leading to abnormalities in the architecture and hyper-keratinization. 3 ‘, 4’, 5,7-Tetrahydroxyisoflavone, also termed orobol, is a metabolite of genistein. Orobol inhibit P. acnes induced increase in IL-6 and IL-1α levels in human keratinocytes (HaCaTs) compared with salicylic acid. Additionally, orobol decrease in IL-1α and IL-6 mRNA levels and inhibit phosphorylation of kinase inhibitor of kappa-B, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, and mitogen-activated protein kinase induced by P. acnes , Finally, the expression of Ki67 decreased by orobol. Thus, improved orobol inflammation and hyper-keratinization caused by P. acnes dead heat and thus has the potential to be used in foods and cosmetics.

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